Management of inferior vena cava tumor thrombus in locally advanced renal...
The diagnosis of renal cell carcinoma is accompanied by intravascular tumor thrombus in up to 10% of cases, of which nearly one-third of patients also have concurrent metastatic disease. Surgical...
View ArticleEffectiveness and safety of nitrofurantoin in outpatient male veterans
Objectives:The aim of the study was to assess both the safety and the effectiveness of nitrofurantoin in male veterans treated for urinary tract infections (UTIs) with varying degrees of renal...
View ArticleAbiraterone in the management of castration-resistant prostate cancer prior...
The treatment armamentarium for metastatic castration-resistant prostate cancer (mCRPC) has increased significantly over the past several years. Approved drugs associated with improved survival...
View ArticleUrinary tract infections in women with stress urinary incontinence treated...
Introduction and objectives:Stress urinary incontinence (SUI) and recurrent urinary tract infections (RUTIs) are highly prevalent diseases. Our purpose was to investigate the relationship between RUTIs...
View ArticleContemporary diagnosis and management of Fournier's gangrene
Fournier’s gangrene, an obliterative endarteritis of the subcutaneous arteries resulting in gangrene of the overlying skin, is a rare but severe infective necrotizing fasciitis of the external...
View ArticleThe efficacy and safety of mirabegron compared with solifenacin in overactive...
Objective:To compare the efficacy and safety of mirabegron 50 mg and solifenacin 5 mg in overactive bladder (OAB) patients dissatisfied with previous antimuscarinic treatment due to lack of efficacy....
View ArticleCytoreductive nephrectomy and its role in the present-day period of targeted...
The beneficial effect of cytoreductive nephrectomy on survival of patients with metastatic renal cell carcinoma in the immunotherapy era was based on two prospective randomized trials. Unfortunately,...
View ArticleClinical experience with everolimus in the second-line treatment of advanced...
Everolimus is an oral inhibitor of mammalian target of rapamycin (mTOR-I) and is currently approved for the treatment of metastatic renal cell carcinoma (mRCC) after failure of first-line vascular...
View ArticleClinical use of the {beta}3 adrenoceptor agonist mirabegron in patients with...
Mirabegron is a β3 adrenoceptor agonist licensed for the treatment of overactive bladder symptoms, such as urinary urgency or urgency incontinence. β3 adrenoceptor activation causes detrusor muscle...
View ArticlePercutaneous biopsy for risk stratification of renal masses
The increased use of abdominal imaging has led to identification of more patients with incidental renal masses, and renal mass biopsy (RMB) has become a popular method to evaluate unknown renal masses...
View ArticleIs whole gland salvage cryotherapy effective as palliative treatment of...
Objectives:Locally advanced prostate cancer may cause several complications such as haematuria, bladder outlet obstruction, and renal failure due to the ureteral obstruction. Various treatments have...
View ArticleTadalafil for lower urinary tract symptoms secondary to benign prostatic...
Tadalafil, a phosphodiesterase type 5 (PDE5) inhibitor, is approved worldwide for the treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia (BPH-LUTS). The purpose of...
View ArticleSterile pyuria: a forgotten entity
Sterile pyuria is a common entity. Yet there are no guidelines to address this issue. We have conducted a systematic review over 20 years and reviewed the results. Guidelines for assessment, diagnosis...
View ArticleCelecoxib for the prevention of nonmuscle invasive bladder cancer: results...
Objectives:New targets and approaches are under investigation for the treatment of nonmuscle invasive bladder cancer (NMIBC). Preclinical data suggest cyclooxygenase-2 (COX-2) as a promising target....
View ArticleTargeting PD-1/PD-L1 in the treatment of metastatic renal cell carcinoma
Immunostimulatory therapies have been a cornerstone of treatment for metastatic renal cell carcinoma (RCC) since the 1990s. However, the use of traditional immunotherapeutic approaches for RCC, such...
View ArticleHistone deacetylase inhibitors in castration-resistant prostate cancer:...
Historically, androgen-deprivation therapy has been the cornerstone for treatment of metastatic prostate cancer. Unfortunately, nearly majority patients with prostate cancer transition to the...
View ArticleTestosterone and prostate cancer: an evidence-based review of pathogenesis...
Testosterone plays a central role in male development and health. Likewise, androgen deficiency, or hypogonadism, is associated with a variety of symptoms including decreased energy, diminished libido...
View ArticleHexaminolevulinate hydrochloride in the detection of nonmuscle invasive...
Clinical trials have shown that hexaminolevulinate (HAL) fluorescence cystoscopy improves the detection of bladder tumors compared with standard white-light cystoscopy, resulting in more efficacious...
View ArticleMuscle-invasive urothelial bladder cancer: an update on systemic therapy
Urothelial carcinoma is a common malignancy that carries a poor prognosis when the disease includes muscle invasion. Metastatic urothelial carcinoma is almost uniformly fatal. The evidence behind...
View ArticleManagement of carcinoma in situ of the bladder: best practice and recent...
Management of carcinoma in situ of the bladder remains a complex and challenging endeavor due to its high rate of recurrence and progression. Although it is typically grouped with other nonmuscle...
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